from a derivative probably of G3817 (meaning a "path"); to trample (literally or figuratively):--tread (down, under foot).
to tread
to trample, crush with the feet
to advance by setting foot upon, tread upon: to encounter successfully the greatest perils from the machinations and persecutions with which Satan would fain thwart the preaching of the gospel
to tread under foot, trample on, i.e. to treat with insult and contempt: to desecrate the holy city by devastation and outrage