from a compound of G1 (as a negative particle) and a derivative of G5087; to set aside, i.e. (by implication) to disesteem, neutralize or violate:--cast off, despise, disannul, frustrate, bring to nought, reject.
to do away with, to set aside, disregard
to thwart the efficacy of anything, nullify, make void, frustrate
